EVALUATION OF PHOSPHATE IN REFRIGERANTS AS A POTENTIAL CAUSE OF HYPERPHOSPHATEMIA BY EXOGENOUS OVERLOAD OF POLYATOMIC ION
Keywords:
Non-alcoholic beverages; Body electrolyte; Chemical bondAbstract
The soda is one of the most consumed products in Brazil. Because it contains phosphate ions in the composition, uncontrolled intake of the phosphorus mineral can cause hyperphosphatemia. Therefore, the objective was to evaluate phosphate in soft drinks of different types and to investigate if they are suitable to be consumed according to the daily recommendation with the aid of the visible spectrophotometry technique for non-alcoholic beverages. According to the results, only guaraná type soda has been in compliance with current legislation, which allows up to 0.07% phosphate, and safe for daily intake for healthy adults. Already the cola-type soda resulted in total disagreement with legislation and completely unsuitable for consumption. Therefore, regulatory agencies should be aware of other risk factors present in the composition of the product as it is a very consumed drink and with high potential that causes hyperphosphatemia.
Downloads
Download data is not yet available.
References
ALONSO, M. B. C. C. Avaliação da densidade mineral óssea, conteúdo mineral ósseo e níveis séricos de cálcio, fósforo e magnésio em ratos submetidos à dieta diária de café e refrigerantes à base de cola e guaraná. 2015. 64 f. Tese (doutorado) - Universidade Estadual de Campinas, Faculdade de Odontologia de Piracicaba, Piracicaba, SP. Disponível em: <http://www.repositorio.unicamp.br/handle/REPOSIP/288533>. Acesso em: 04 ago. 2019.
APOVIAN, C. M. Sugar-sweetened soft drinks, obesity, and type 2 diabetes. Jama, v. 292, n. 8, p. 978-979, 2004.
BNDES. O setor de bebidas no Brasil. Banco Nacional de Desenvolvimento Econômico e Social (BNDES). São Paulo, 2014.
BASU, S. et al. Relationship of soft drink consumption to global overweight, obesity, and diabetes: a cross-national analysis of 75 countries. American journal of public health, v. 103, n. 11, p. 2071-2077, 2013.
BIGGS, S.; DUNN, J.; YAO, M. Beyond the sugar: Chemicals in sodas and their link to systemic diseases and oral health. 2017.
BRASIL. Lei nº 6.437, de 20 de agosto de 1977: Configura infrações à legislação sanitária federal, estabelece as sanções respectivas, e dá outras providências. Diário Oficial da União, 1977.
CHAVES, Otaviana Cardoso et al. Soft drink consumption and body mass index in Brazilian adolescents: National Adolescent Student Health Survey. Revista Brasileira de Epidemiologia, v. 21, 2018.
DA SILVA, A. L. A.; JUNIOR, A. I. S.; DE CASTRO, J. P.; BENTO, R. M. A. TREINAMENTO DE PROFESSORES EM ANÁLISE INSTRUMENTAL – ESPECTROFOTOMETRIA. 53º Congresso Brasileiro de Quimica – 14 a 18 de Outubro de 2013. Rio de Janeiro/RJ. Associação Brasileira de Química. 2013.
DHINGRA, Ravi et al. Relations of serum phosphorus and calcium levels to the incidence of cardiovascular disease in the community. Archives of internal medicine, v. 167, n. 9, p. 879-885, 2007.
FELIX, L. C. M.; MEDEIROS, V. C. M.; MOLINA, V. B. C. Análise do conhecimento e consumo de alimentos fontes de fósforo por pacientes portadores de insuficiência renal crônica em tratamento dialítico. Braspen J, v. 33, n. 1, p. 15-20, 2018.
INSTITUTO ADOLFO LUTZ Normas Analíticas do Instituto Adolfo Lutz. v.1:
LOH, T. P.; SAW, S.; SETHI, S. K. Hyperphosphatemia in a 56-year-old man with hypochondrial pain. Clinical chemistry, v. 56, n. 6, p. 892-895, 2010.
LUDWIG, D. S.; PETERSON, K. E.; GORTMAKER, S. L. Relation between consumption of sugar-sweetened drinks and childhood obesity: a prospective, observational analysis. The Lancet, v. 357, n. 9255, p. 505-508, 2001.
MATEO, C. R. El fosfato marca la diferencia. XVI Edición del Carnaval de Química. Hablando de Ciencia. 2012. Disponível em: https://www.hablandodeciencia.com/articulos/2012/06/28/sutiles-cambios-quimicos-drasticas-consecuencias-para-la-funcion-de-las-proteinas/. Acesso em: 01 ago 2019.
Métodos químicos e físicos para análise de alimentos. Sao Paulo: IMESP, 3. ed., 1985. p 33.
MOE, S. M. Disorders involving calcium, phosphorus, and magnesium. Primary Care: Clinics in Office Practice, v. 35, n. 2, p. 215-237, 2008.
MOSTELLAR, M. E.; TUTTLE, E. P. Effects of alkalosis on plasma concentration and urinary excretion of inorganic phosphate in man. The Journal of clinical investigation, v. 43, n. 1, p. 138-149, 1964.
NOORI, Nazanin et al. Association of dietary phosphorus intake and phosphorus to protein ratio with mortality in hemodialysis patients. Clinical Journal of the American Society of Nephrology, v. 5, n. 4, p. 683-692, 2010.
OHNISHI, Mutsuko; RAZZAQUE, M. Shawkat. Dietary and genetic evidence for phosphate toxicity accelerating mammalian aging. The FASEB Journal, v. 24, n. 9, p. 3562-3571, 2010.
OLIVEIRA, P. H. D.; LUSTOSA, P. R. B.; SALES, I. C. H. Comportamento de custos como parâmetro de eficiência produtiva: uma análise empírica da companhia Vale do Rio Doce antes e após a privatização. Revista Universo Contábil, v. 3, n. 3, p. 54-70, 2007.
ORIAS, M.; MAHNENSMITH, R. L.; PERAZELLA, M. A. Extreme hyperphosphatemia and acute renal failure after a phosphorus-containing bowel regimen. American journal of nephrology, v. 19, n. 1, p. 60-63, 1999.
PRINCE, M. J. et al. Hyperphosphatemic tumoral calcinosis: association with elevation of serum 1, 25-dihydroxycholecalciferol concentrations. Annals of Internal Medicine, v. 96, n. 5, p. 586-591, 1982.
RITZ, Eberhard et al. Phosphate additives in food—a health risk. Deutsches Ärzteblatt International, v. 109, n. 4, p. 49, 2012.
SCHAEFER, K. Unsatisfactory control of serum phosphate: Why is it so common and what can be done?. 1994.
SHAMAN, A. M.; KOWALSKI, S. R. Hyperphosphatemia management in patients with chronic kidney disease. Saudi Pharmaceutical Journal, v. 24, n. 4, p. 494-505, 2016.
SHI, Z. et al. Soft drink consumption and multimorbidity among adults. Clinical nutrition ESPEN, v. 10, n. 2, p. e71-e76, 2015.
SILVA, A. C. S.; PINHEIRO, S. V. B.; SOUTO, M. F. O. Distúrbios de cálcio e fósforo na infância. Rev Med Minas Gerais, v. 16, n. 1, p. 26-37, 2006.
SILVA, D. C. G. da et al. Consumo de bebidas açucaradas e fatores associados em adultos. Ciência & Saúde Coletiva, v. 24, p. 899-906, 2019.
URIBARRI, J. Phosphorus homeostasis in normal health and in chronic kidney disease patients with special emphasis on dietary phosphorus intake. In: Seminars in dialysis. 2007. p. 295-301.
WILLETT, W. Eat, drink, and be healthy: the Harvard Medical School guide to healthy eating. Simon and Schuster, 2017.
ZHENG, H.; HUANG, L.; ROSS JR, W. Reducing Obesity by Taxing Soft Drinks: Tax Salience and Firms’ Strategic Responses. Journal of Public Policy & Marketing, p. 0743915619845424, 2019.
APOVIAN, C. M. Sugar-sweetened soft drinks, obesity, and type 2 diabetes. Jama, v. 292, n. 8, p. 978-979, 2004.
BNDES. O setor de bebidas no Brasil. Banco Nacional de Desenvolvimento Econômico e Social (BNDES). São Paulo, 2014.
BASU, S. et al. Relationship of soft drink consumption to global overweight, obesity, and diabetes: a cross-national analysis of 75 countries. American journal of public health, v. 103, n. 11, p. 2071-2077, 2013.
BIGGS, S.; DUNN, J.; YAO, M. Beyond the sugar: Chemicals in sodas and their link to systemic diseases and oral health. 2017.
BRASIL. Lei nº 6.437, de 20 de agosto de 1977: Configura infrações à legislação sanitária federal, estabelece as sanções respectivas, e dá outras providências. Diário Oficial da União, 1977.
CHAVES, Otaviana Cardoso et al. Soft drink consumption and body mass index in Brazilian adolescents: National Adolescent Student Health Survey. Revista Brasileira de Epidemiologia, v. 21, 2018.
DA SILVA, A. L. A.; JUNIOR, A. I. S.; DE CASTRO, J. P.; BENTO, R. M. A. TREINAMENTO DE PROFESSORES EM ANÁLISE INSTRUMENTAL – ESPECTROFOTOMETRIA. 53º Congresso Brasileiro de Quimica – 14 a 18 de Outubro de 2013. Rio de Janeiro/RJ. Associação Brasileira de Química. 2013.
DHINGRA, Ravi et al. Relations of serum phosphorus and calcium levels to the incidence of cardiovascular disease in the community. Archives of internal medicine, v. 167, n. 9, p. 879-885, 2007.
FELIX, L. C. M.; MEDEIROS, V. C. M.; MOLINA, V. B. C. Análise do conhecimento e consumo de alimentos fontes de fósforo por pacientes portadores de insuficiência renal crônica em tratamento dialítico. Braspen J, v. 33, n. 1, p. 15-20, 2018.
INSTITUTO ADOLFO LUTZ Normas Analíticas do Instituto Adolfo Lutz. v.1:
LOH, T. P.; SAW, S.; SETHI, S. K. Hyperphosphatemia in a 56-year-old man with hypochondrial pain. Clinical chemistry, v. 56, n. 6, p. 892-895, 2010.
LUDWIG, D. S.; PETERSON, K. E.; GORTMAKER, S. L. Relation between consumption of sugar-sweetened drinks and childhood obesity: a prospective, observational analysis. The Lancet, v. 357, n. 9255, p. 505-508, 2001.
MATEO, C. R. El fosfato marca la diferencia. XVI Edición del Carnaval de Química. Hablando de Ciencia. 2012. Disponível em: https://www.hablandodeciencia.com/articulos/2012/06/28/sutiles-cambios-quimicos-drasticas-consecuencias-para-la-funcion-de-las-proteinas/. Acesso em: 01 ago 2019.
Métodos químicos e físicos para análise de alimentos. Sao Paulo: IMESP, 3. ed., 1985. p 33.
MOE, S. M. Disorders involving calcium, phosphorus, and magnesium. Primary Care: Clinics in Office Practice, v. 35, n. 2, p. 215-237, 2008.
MOSTELLAR, M. E.; TUTTLE, E. P. Effects of alkalosis on plasma concentration and urinary excretion of inorganic phosphate in man. The Journal of clinical investigation, v. 43, n. 1, p. 138-149, 1964.
NOORI, Nazanin et al. Association of dietary phosphorus intake and phosphorus to protein ratio with mortality in hemodialysis patients. Clinical Journal of the American Society of Nephrology, v. 5, n. 4, p. 683-692, 2010.
OHNISHI, Mutsuko; RAZZAQUE, M. Shawkat. Dietary and genetic evidence for phosphate toxicity accelerating mammalian aging. The FASEB Journal, v. 24, n. 9, p. 3562-3571, 2010.
OLIVEIRA, P. H. D.; LUSTOSA, P. R. B.; SALES, I. C. H. Comportamento de custos como parâmetro de eficiência produtiva: uma análise empírica da companhia Vale do Rio Doce antes e após a privatização. Revista Universo Contábil, v. 3, n. 3, p. 54-70, 2007.
ORIAS, M.; MAHNENSMITH, R. L.; PERAZELLA, M. A. Extreme hyperphosphatemia and acute renal failure after a phosphorus-containing bowel regimen. American journal of nephrology, v. 19, n. 1, p. 60-63, 1999.
PRINCE, M. J. et al. Hyperphosphatemic tumoral calcinosis: association with elevation of serum 1, 25-dihydroxycholecalciferol concentrations. Annals of Internal Medicine, v. 96, n. 5, p. 586-591, 1982.
RITZ, Eberhard et al. Phosphate additives in food—a health risk. Deutsches Ärzteblatt International, v. 109, n. 4, p. 49, 2012.
SCHAEFER, K. Unsatisfactory control of serum phosphate: Why is it so common and what can be done?. 1994.
SHAMAN, A. M.; KOWALSKI, S. R. Hyperphosphatemia management in patients with chronic kidney disease. Saudi Pharmaceutical Journal, v. 24, n. 4, p. 494-505, 2016.
SHI, Z. et al. Soft drink consumption and multimorbidity among adults. Clinical nutrition ESPEN, v. 10, n. 2, p. e71-e76, 2015.
SILVA, A. C. S.; PINHEIRO, S. V. B.; SOUTO, M. F. O. Distúrbios de cálcio e fósforo na infância. Rev Med Minas Gerais, v. 16, n. 1, p. 26-37, 2006.
SILVA, D. C. G. da et al. Consumo de bebidas açucaradas e fatores associados em adultos. Ciência & Saúde Coletiva, v. 24, p. 899-906, 2019.
URIBARRI, J. Phosphorus homeostasis in normal health and in chronic kidney disease patients with special emphasis on dietary phosphorus intake. In: Seminars in dialysis. 2007. p. 295-301.
WILLETT, W. Eat, drink, and be healthy: the Harvard Medical School guide to healthy eating. Simon and Schuster, 2017.
ZHENG, H.; HUANG, L.; ROSS JR, W. Reducing Obesity by Taxing Soft Drinks: Tax Salience and Firms’ Strategic Responses. Journal of Public Policy & Marketing, p. 0743915619845424, 2019.
Downloads
Published
2019-10-29
Issue
Section
Artigo Científico Original
How to Cite
EVALUATION OF PHOSPHATE IN REFRIGERANTS AS A POTENTIAL CAUSE OF HYPERPHOSPHATEMIA BY EXOGENOUS OVERLOAD OF POLYATOMIC ION. (2019). Colloquium Exactarum. ISSN: 2178-8332, 11(3), 54-62. https://journal.unoeste.br/index.php/ce/article/view/3260