POTASSIUM DICHROMATE INTAKE INDUCES MORPHOLOGICAL CHANGES IN RAT’S CARDIOMYOCYTES
Abstract
The aim of this study was to analyze the effects of diet’s potassium dichromate supplementation on cardiac muscle tissue morphology in rats. Forty male rats were used, divided into G0: basal diet, G1: basal diet + 12 mg.kg-1 potassium dichromate, G2: basal diet + 24 mg.kg-1 and G3: basal diet + 36 mg.kg -1 for 90 days. The animals were euthanized, with heart extraction for morphological analysis and fractal dimension analysis. Anova One-Way, Kruskall-Wallis, Tukey and Dunn were used to compare the results, with p<0.05. There is no differences on body mass and heart mass. G1 showed greater tissue inflammation of compared to G2 and G0. It was concluded that potassium dichromate generates morphological changes by proinflammatory effect in rat cardiomyocytes.
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