Postnatal exposure to air pollutants PM≤2,5 as risk factor for the development of depression and anxiety: an experimental study
Abstract
The purpose of study was to evaluate the behavioral changes of male and female adult rats exposed to fine and ultrafine particulate matter (PM≤2,5) suspended in air pollution during development. Wistar rats aged 7 days postnatal were exposed to the chamber of an atmospheric particle concentrator. Open field tests and sucrose preference tests were performed to assess the presence of anxiety and depression behaviors. Male rats from the pollution group showed reduced locomotor activity and length of stay in the open field center when compared to the control group males. The sucrose preference test showed statistical significance between the pollution and control groups, and among the males of the pollution and control group. The study concluded that exposure to PM≤2.5 causes behavioral changes characteristic of depression and anxiety in adult male rats exposed during the developmental period.
Downloads
Downloads
Published
Issue
Section
License
Os artigos submetidos à revista Colloquium Vitae estão licenciados conforme CC BY-NC-ND. Para mais informações sobre essa forma de Licenciamento, consulte: http://creativecommons.org/licenses/by-nc-nd/4.0/.
A disponibilização é gratuita na Internet, para que os usuários possam ler, fazer download, copiar, distribuir, imprimir, pesquisar ou referenciar o texto integral dos documentos, processá-los para indexação, utilizá-los como dados de entrada de programas para softwares, ou usá-los para qualquer outro propósito legal, sem barreira financeira, legal ou técnica.
